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Belsomra (suvorexant) is used to treat insomnia in adults. It’s helpful for those who have a hard time falling asleep or staying asleep. This sleep medication belongs to the drug class called orexin receptor antagonists. You take a dosage within 30 minutes of bedtime as needed for sleep. It’s common to feel drowsy the next day as a side effect. It’s available as a brand-name medication only.

This medication is used to treat a certain sleep problem (insomnia). It may help you fall asleep and stay asleep longer, so you can get a better night’s rest. Suvorexant belongs to a class of drugs known as sedative-hypnotics.

If your insomnia continues for longer than 7 to 10 days after starting treatment, talk to your doctor to see if you need other treatment.

How Belsomra (suvorexant) works

elsomra (suvorexant) is an orexin receptor antagonist. It works by blocking the action of orexin. Orexin is a chemical in the brain that plays a role in the sleep cycle and helps with wakefulness. By blocking orexin, Belsomra (suvorexant) can help people sleep.

The dosage is based on your medical condition, response to treatment, and other medications you may be taking. Be sure to tell your doctor and pharmacist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).

What is Belsomra for sleep?

Belsomra (suvorexant) is an oral medication approved by the U.S. Food and Drug Administration (FDA) in 2014 to treat insomnia in adults, including difficulties with sleep onset (falling asleep) and/or sleep maintenance (staying asleep). It’s also prescribed off-label to treat opioid use disorder (OUD).

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Belsomra belongs to a class of drugs called orexin receptor antagonists (ORAs), which work by suppressing the activity of orexin, a neurotransmitter that promotes wakefulness. By blocking orexin, Belsomra helps regulate the sleep-wake cycle, making it easier to fall asleep and stay asleep.

Belsomra is only available as a brand-name drug. There’s no generic available.

How does Belsomra for sleep work?

Belsomra works by inhibiting the action of orexin, a brain chemical responsible for keeping you awake. Unlike some sleep aids that work by depressing the central nervous system (CNS), Belsomra targets a specific pathway involved in wakefulness to allow for a more natural sleep process.

Clinical trials show that Belsomra can help reduce the time it takes to fall asleep (sleep latency) and improve total sleep time. In a survey of insomnia patients, those taking Belsomra reported getting 1 more hour of sleep per night and falling asleep about 10 minutes faster.

People who take Belsomra also report better sleep quality and daytime functioning.

Belsomra is also proven effective in people with certain types of insomnia, including those who work night shifts or who are going through menopause. For example, a study of shift workers found that Belsomra helped them get 2 more hours of sleep during the day. In a study of women with vasomotor symptom-associated insomnia (insomnia caused by hot flashes and night sweats), Belsomra significantly reduced nighttime awakenings.

Who can take Belsomra for sleep?

Belsomra is FDA-approved for adults experiencing insomnia characterized by difficulty falling asleep or staying asleep. It’s generally considered safe for long-term use when used as directed. But, it may not be suitable for everyone, including those with narcolepsy, severe obstructive sleep apnea (OSA), or severe chronic obstructive pulmonary disease (COPD).

A healthcare provider can determine if Belsomra is right for you based on your medical history and insomnia symptoms.

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Do not take a dose of this drug unless you have time for a full night’s sleep of at least 7 hours. If you have to wake up before that, you may have some memory loss and may have trouble safely doing any activity that requires alertness, such as driving or operating machinery. (See also Precautions section.) Do not increase your dose, take it more often, or use it for longer than prescribed. Your condition will not improve any faster, and your risk of side effects will increase.

Do not take this medication with alcohol, or if you have had alcohol that day, especially in the evening before bed. Also, do not take this medication with other drugs to help you sleep.

When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.

Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.

Unusual dreams may occur. If this effect persists or worsens, tell your doctor or pharmacist promptly.

Suvorexant may make you sleepy during the day. Tell your doctor if you have daytime drowsiness. Your dose may need to be adjusted.

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Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.

Tell your doctor right away if you have any serious side effects, including: mental/mood changes (such as depression, thoughts of suicide), temporary weakness in your legs.

This medication may cause sleep paralysis, which is a temporary inability to move or talk (for up to several minutes) while you are going to sleep or waking up.

Rarely, after taking this drug, people have gotten out of bed and driven vehicles while not fully awake (“sleep-driving”). People have also sleepwalked, prepared/eaten food, made phone calls, or had sex while not fully awake. Often, these people do not remember these events. This problem can be dangerous to you or to others. If you find out that you have done any of these activities after taking this medication, tell your doctor right away. Your risk is increased if you use alcohol or other medications that can make you drowsy while taking suvorexant.

A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

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Dosage	5mg, 10mg, 15mg, 20mg
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